Setting New Benchmarks in Proteomics
Proteoforms are the true drivers of molecular function
Proteoforms represent the myriad molecular forms of proteins that arise from genetic variation, alternative splicing, and post-translational modifications, creating a rich tapestry of functional diversity within the cell. Each proteoform possesses unique biological activities and interactions, making them critical targets for understanding disease mechanisms and developing precision therapies. Harnessing the power of high-throughput proteomics, our cutting-edge technology at ProQomics offers unprecedented insights into Proteoforms dynamics, enabling revolutionary advances in biomedical research and drug discovery.
A revolutionary platform that combines the advantage of two state of the art techniques
At ProQomics, we seamlessly integrate two cutting-edge protein quantification technologies: multiplexed immuno arrays and LC-MS, overcoming their individual limitations to forge a powerful high-throughput technique. Our unique approach allows for the direct measurement of proteoforms, rather than relying on proxy measurements, setting a new standard in the field. This innovation not only increases the throughput but also enhances the sensitivity, offering an unparalleled tool for precise proteoform analysis
Advantages of ProQomics Platform
High confidence proteoform data
Can customize to any number of proteofroms
Quantitation of over 15000 proteoforms
True quantitation using internal and reference standards
Quantitation at sub Atto molar levels
1000 Proteoforms per minute
First platform for high throughput quantitation of proteoforms
Highly reproducible mass spectrometry analysis
Quantitation by competitive binding offers broad dynamic range
Simple workflow
Sample preprocessing
Proteins are extracted from the sample and proteolyzed using standard techniques.
Proteoform enrichment
Extracted samples are incubated with proQomics reagent for enrichment.
Reagent processing
ProQomics reagents are processed by ProQFiler and read by the mass spectrometry
Data analysis
Simple and straight forward data analysis