Providing solutions for today’s challenges and tomorrow’s imperatives
Drug discovery
ProQomics enables the precise quantitation of proteoforms, helping researchers uncover new targets that are modulated in disease states. Our platform provides the detailed protein-level data needed to confidently pursue novel targets with therapeutic potential.
ProQomics platform supports assay development by providing high-resolution data on proteoform interactions and activities. Our technology allows for the development of robust, reproducible assays that can accurately measure the effects of potential therapeutics on target proteoforms, ensuring that assays are both sensitive and specific.
ProQomics high-throughput quantitation of proteoforms enables researchers to evaluate the efficacy and specificity of multiple leads rapidly. By providing detailed insights into how each compound affects proteoform expression and function, our platform aids in the selection of the most promising therapeutic candidates.
ProQomics supports the discovery and validation of proteoform-based biomarkers that can be used throughout the drug development process. Our platform provides the sensitivity and precision needed to identify and quantify biomarkers that reflect drug activity and patient response.
ProQomics’ technology provides the proteomic insights needed to support IND submissions, including detailed analyses of target engagement, biomarker validation, and toxicology. Our platform ensures that your IND filing is backed by robust, high-quality data.
ProQomics' platform aids in trial design by providing insights into proteoform dynamics, helping to define patient stratification criteria, identify relevant biomarkers, and optimize dosing strategies. Our technology ensures that clinical trials are informed by the most accurate and comprehensive proteomic data available.
ProQomics’ platform enables detailed toxicological studies by quantifying proteoforms that are indicative of drug-induced toxicity. Our technology provides the sensitivity and precision needed to detect early signs of toxicity, helping to ensure the safety of drug candidates before they advance to clinical trials.
ProQomics' platform supports drug repurposing efforts by revealing new proteoform targets that are modulated by existing drugs. Our high-throughput technology enables researchers to quickly identify potential new uses for approved drugs, offering a faster path to market for repurposed therapeutics.
Clinical / Basic research
Understanding the underlying mechanisms of disease is crucial for developing targeted therapies and effective treatments. ProQomics platform enables researchers to explore the complexities of proteoforms, offering insights into how protein modifications drive disease processes. By revealing the intricate pathways and interactions involved, our technology supports the identification of novel therapeutic targets and biomarkers that can lead to more effective interventions.
Epigenetic modifications can dramatically alter protein function and are key regulators of gene expression. ProQomics allows for the precise quantitation of proteoforms influenced by epigenetic changes, providing a deeper understanding of how these modifications contribute to health and disease. Our platform supports research into the dynamic interplay between epigenetics and protein function, paving the way for breakthroughs in personalized medicine and targeted treatments.
Biologics manufacturing
Ensuring the quality and consistency of biologics is paramount in manufacturing. ProQomics’ platform offers high-resolution quantitation of proteoforms, enabling precise quality control throughout the production process. Our technology helps manufacturers monitor critical quality attributes, ensuring that biologics are produced to the highest standards of safety and efficacy.
Allergen detection is a crucial aspect of biologics manufacturing, particularly in the production of therapeutic proteins. ProQomics' platform allows for the sensitive detection and quantitation of allergenic proteoforms, ensuring that biologic products are free from contaminants that could trigger adverse reactions. Our technology supports the development of safer biologics by providing comprehensive allergen monitoring.
Artificial intelligence
ProQomics platform provides high-throughput proteomic data that can be seamlessly integrated with other omics data using artificial intelligence (AI). This multi-omics approach enables a more holistic understanding of biological processes and disease mechanisms, leading to more accurate predictions and discoveries.
Transomics involves the integration of data across different biological scales, from genes to proteins to metabolites. ProQomics platform plays a vital role in transomics research by providing detailed proteoform data that bridges the gap between genetic variation and phenotypic outcomes. Our technology enables researchers to construct comprehensive models of biological systems, leading to new insights into how molecular changes drive disease.
Understanding causal relationships between molecular events is crucial for developing effective treatments. ProQomics high-resolution quantitation of proteoforms, combined with AI-driven data analysis, helps researchers identify causal links between protein modifications and disease states. Our platform supports the discovery of causal mechanisms that can be targeted with therapeutic interventions.
Large Language Models (LLMs) are increasingly used in bioinformatics to interpret complex datasets and generate hypotheses. ProQomics platform generates vast amounts of high-quality proteomic data that can be fed into LLMs for advanced analysis and prediction. By combining our proteoform quantitation with LLM-driven insights, researchers can accelerate the discovery process and uncover novel biological relationships.